Journal
ADVANCES IN COLLOID AND INTERFACE SCIENCE
Volume 167, Issue 1-2, Pages 49-62Publisher
ELSEVIER
DOI: 10.1016/j.cis.2010.10.006
Keywords
Biopolymers; Nanoparticles; Microparticles; Protein; Polysaccharide; Delivery systems; Complexation; Coacervation; Electrostatics
Categories
Funding
- Cooperative State Research, Extension, Education Service
- United State Department of Agriculture
- Massachusetts Agricultural Experiment Station
- United States Department of Agriculture, CREES
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Functional biopolymer nanoparticles or microparticles can be formed by heat treatment of globular protein-ionic polysaccharide electrostatic complexes under appropriate solution conditions. These biopolymer particles can be used as encapsulation and delivery systems, fat mimetics, lightening agents, or texture modifiers. This review highlights recent progress in the design and fabrication of biopolymer particles based on heating globular protein-ionic polysaccharide complexes above the thermal denaturation temperature of the proteins. The influence of biopolymer type, protein-polysaccharide ratio, pH, ionic strength, and thermal history on the characteristics of the biopolymer particles formed is reviewed. Our current understanding of the underlying physicochemical mechanisms of particle formation and properties is given. The information provided in this review should facilitate the rational design of biopolymer particles with specific physicochemical and functional attributes, as well as stimulate further research in identifying the physicochemical origin of particle formation. (C) 2010 Elsevier B.V. All rights reserved.
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