Journal
ADVANCES IN COLLOID AND INTERFACE SCIENCE
Volume 145, Issue 1-2, Pages 1-22Publisher
ELSEVIER
DOI: 10.1016/j.cis.2008.07.004
Keywords
Protein separation; Membrane technology; Membrane filtration; Microfiltration; Ultrafiltration; Electro-ultrafiltration; Membrane contactor; Membrane chromatography
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Funding
- Department of Biotechnology, Government of India [BT/PR5994/PID/06/268/2005]
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Membrane processes are increasingly reported for various applications in both upstream and downstream technology, such as microfiltration, ultrafiltration, emerging processes as membrane chromatography, high performance tangential flow filtration and electrophoretic membrane contactor. Membrane-based processes are playing critical role in the field of separation/purification of biotechnological products. Membranes became an integral part of biotechnology and improvements in membrane technology are now focused on high resolution of bioproduct. In bioseparation. applications of membrane technologies include protein production/purification, protein-virus separation. This manuscript provides an overview of recent developments and published literature in membrane technology, focusing on special characteristics of the membranes and membrane-based processes that are now used for the production and purification of proteins. (C) 2008 Elsevier B.V. All rights reserved.
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