Journal
ADVANCES IN CHRONIC KIDNEY DISEASE
Volume 21, Issue 3, Pages 260-266Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.ackd.2014.03.009
Keywords
Diabetic kidney disease; CKD; ESRD; Risk factors; Epidemiology
Categories
Funding
- Folkhalsan Research Foundation, the Academy of Finland [134379]
- Wilhelm and Else Stockmann Foundation
- Liv och Halsa Foundation,
- Novo Nordisk Foundation
- Eli Lilly
- Roche
- Academy of Finland (AKA) [134379, 134379] Funding Source: Academy of Finland (AKA)
Ask authors/readers for more resources
Prevalence rates of diabetic kidney disease (DKD) are increasing in parallel with the incidence rates of diabetes mellitus. DKD has already become a significant health problem worldwide. Without radical improvements in prevention and treatment, DKD prevalence will continue to climb. The pathogenesis of DKD is complex and multifactorial, with genetic and environmental factors involved. Several nonmodifiable risk factors contribute to DKD, including genetics, sex, age, age at onset, and duration of diabetes. However, there are also several modifiable risk factors that have a strong effect on the risk of DKD. Traditional modifiable factors include glycemic control, blood pressure, lipids, and smoking. Other recently discovered modifiable risk factors include chronic low-grade inflammation, advanced glycation end products, and lack of physical activity. Efficient management of these modifiable risk factors may improve the prognosis of diabetic patients at risk of DKD. (C) 2014 by the National Kidney-Foundation, Inc. Albrights reserved:
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available