Iron-Catalyzed Ring-Opening/Allylation of Cyclobutanone Oxime Esters with Allylic Sulfones

An iron-catalyzed radical allylation of cyclobutanone oxime esters with allylic sulfones via C-C bond cleavage is reported. This protocol provides a straight-forward approach to cyanoalkylated alkenes with good functional group tolerance and high regioselectivity. Furthermore, this reaction can be further expanded to ring-opening of less-strained cyclopentanone oxime esters, leading to desired cyanoalkylated alkenes in good yields.