4.7 Review

Recent Advances in Ruthenium(II)-Catalyzed C-H Bond Activation and Alkyne Annulation Reactions

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 361, Issue 4, Pages 654-672

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201800755

Keywords

C-H activation; annulation reactions; heterocycles; ruthenium catalysis

Funding

  1. UGC
  2. SERB-New Delhi
  3. SERB, New Delhi [GPP-0303 (YSS/2014/001018)]
  4. CSIR-New Delhi [OLP-2002]

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In the last few decades, the transition metal-catalyzed activation of inert C-H bonds has led to a fundamental change in the field of synthetic chemistry. Most of these C-H activation reactions deal with simple functionalizations or additions. However, recent years have witnessed an increase of the transition metal-catalyzed activation of C-H bond and annulation reactions. These annulation reactions are appealing to the organic chemist as they afford highly valuable cyclic compounds in a rapid and sustainable manner from readily available compounds. This review article attempts to highlight the recent advances in the ruthenium metal-catalyzed C-H bond activation and alkyne annulation reactions.

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