Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 356, Issue 17, Pages 3505-3509Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201400185
Keywords
amino acids; biocatalysis; coupled enzyme reaction; deracemization; transaminases
Categories
Funding
- Advanced Biomass R&D Center through the National Research Foundation of Korea - Ministry of Education, Science and Technology [ABC-2011-0031358]
Ask authors/readers for more resources
Biocatalytic deracemization of amino acids without relying on oxidase-based deamination of an unwanted enantiomer was demonstrated by coupling alpha- and omega-transaminases displaying opposite stereoselectivity. This strategy employs isopropylamine and a keto acid as cosubstrates and is free of generation of hydrogen peroxide which is troublesome in the conventional oxidase-based methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
