Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 356, Issue 2-3, Pages 411-415Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201300535
Keywords
aerobic conditions; copper; glycine derivatives; indoles; oxidative coupling
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Funding
- National Natural Science Foundation of China [21262029, 21002080]
- Natural Science Foundation of Gansu Province [1107RJYA026]
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A simple and efficient copper(I) chloride-catalyzed aerobic oxidative coupling of glycine derivatives (glycine esters, glycine amides and short peptides) with indoles has been developed. The reaction is performed in the absence of any other additives under mild conditions and only requires simple copper salts as a catalyst and oxygen as a co-oxidant.
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