Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 356, Issue 6, Pages 1172-1198Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201301038
Keywords
asymmetric catalysis; benzofuranones; organocatalysis; stereoselectivity
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Funding
- National Basic Research Program of China (973 Program [2012CB821600, 2010CB833300]
- National Natural Science Foundation of China [21172112, 21390400, 21172118]
- State Key Laboratory on Elemento-organic Chemistry (Nankai University, China)
- Program for New Century Excellent Talents in University [NCET-12-0279]
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The chiral benzofuranone structural motif is a prominent feature in many natural products, which exhibit a broad range of biological and pharmaceutical activities. In the past few years, a survey of chiral benzofuranone derivatives based on asymmetric catalysis reveals an increasing number of papers, which reflects the latest achievements to facilitate the synthesis of sufficient quantities of related compounds as potential medicinal agents and biological probes. Recent advances in this area are summarized and classified according to the structure of the starting substrate.
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