4.7 Review

Direct Trifluoromethylation of the CH Bond

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 355, Issue 4, Pages 617-626

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201200764

Keywords

catalysis; CH activation; copper; palladium; trifluoromethylation

Funding

  1. NSFC [21272075]
  2. Yingcai Program of ECNU
  3. Shanghai Pujiang Program [12PJ402500]
  4. Shanghai Talent Development Support [2011022]
  5. China Postdoctoral Science Foundation [2012M520858]

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Trifluoromethylation meets CH activation: after transition metal-catalyzed trifluoromethylation became more and more popular, trifluoromethylation via CH activation is now emerging as the latest attraction. Several pioneering examples and their mechanisms are discussed in this review.

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