4.7 Article

Zheda-Phos for General -Monoarylation of Acetone with Aryl Chlorides

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 355, Issue 7, Pages 1255-1259

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201300207

Keywords

acetone; CCl bond activation; monoarylation; phosphines

Funding

  1. National Basic Research Program of China [2009CB825300]
  2. National Natural Science Foundation of China [21172192]

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A new, readily available, and air-stable monophosphine ligand, i.e., Zheda-Phos, has been developed for the general and highly effective palladium-catalyzed monoarylation of acetone with aryl chlorides. The reaction rate is of first-order dependence with the aryl chloride.

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