4.7 Article

Sodium Sulfinate-Mediated trans-Stilbene Formation from Benzylic Halides

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 354, Issue 10, Pages 1914-1918

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201200167

Keywords

benzylic halides; elimination; sodium sulfinates; stilbenes

Funding

  1. National Natural Science Foundation of China [21172185]
  2. Hunan Provincial Natural Science Foundation of China [11JJ1003]
  3. New Century Excellent Talents in University from Ministry of Education of China [NCET-11-0974]
  4. Scientific Research Foundation for Returned Scholars, Ministry of Education of China [2011-1568]

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A convenient and efficient method for the synthesis of various symmetrical and non-symmetrical trans-stilbene derivatives from benzylic halides in the absence of any transition metals is described. Sodium sulfinates played an important role in this transformation. Various functional groups were well tolerated under the optimized reaction conditions.

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