4.7 Article

Copper-Catalyzed Cyanation of Aryl Iodides with Malononitrile: An Unusual Cyano Group Transfer Process from C(sp3) to C(sp2)

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 354, Issue 4, Pages 589-592

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201100836

Keywords

catalysis; C?C activation; copper; cyano group transfer

Funding

  1. Natural Science Foundation of China [21072132]
  2. Sichuan Provincial Foundation [08ZQ026-041]
  3. Ministry of Education [NCET-10-0581]

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An unusual copper-catalyzed cyanation of aryl iodides to form aryl nitriles by cyano group transfer from C(sp3) to C(sp2) carbon atoms is reported and proceeds to give yields of up to 86%.

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