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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Directed evolution of enantioselective enzymes: Iterative cycles of CASTing for probing protein-sequence space
MT Reetz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Kinetic resolution of 4-hydroxy-2-ketones catalyzed by a Baeyer-Villiger monooxygenase
Anett Kirschner et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
Simulation modeling of pooling for combinatorial protein engineering
KM Polizzi et al.
JOURNAL OF BIOMOLECULAR SCREENING (2005)
Converting phenylacetone monooxygenase into phenylcyclohexanone monooxygenase by rational design: Towards practical Baeyer-Villiger monooxygenases
M Bocola et al.
ADVANCED SYNTHESIS & CATALYSIS (2005)
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site
LX Tang et al.
BIOCHEMISTRY (2005)
Directed evolution of an amine oxidase for the preparative deracemisation of cyclic secondary amines
R Carr et al.
CHEMBIOCHEM (2005)
Discovery of a thermostable Baeyer-Villiger monooxygenase by genome mining
MW Fraaije et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2005)
Expanding the range of substrate acceptance of enzymes: Combinatorial active-site saturation test
MT Reetz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates
WA Greenberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Environmental genome shotgun sequencing of the Sargasso Sea
JC Venter et al.
SCIENCE (2004)
Exploring nitrilase sequence space for enantioselective catalysis
DE Robertson et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2004)
Crystal structure of a Baeyer-Villiger monooxygenase
E Malito et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Making optimal use of empirical energy functions: Force-field parameterization in crystal space
E Krieger et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Protein structure prediction and analysis using the Robetta server
DE Kim et al.
NUCLEIC ACIDS RESEARCH (2004)
Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions
MT Reetz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Directed evolution of cyclohexanone monooxygenases: Enantioselective biocatalysts for the oxidation of prochiral thioethers
MT Reetz et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases
NM Kamerbeek et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2004)
A molecular mechanism of enantiorecognition of tertiary alcohols by carboxylesterases
E Henke et al.
CHEMBIOCHEM (2003)
Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions
M Wada et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2003)
Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution
GJ Williams et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Molecular recognition in (+)-α-pinene oxidation by cytochrome P450cam
SG Bell et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Directed evolution of an amine oxidase possessing both broad substrate specificity and high enantioselectivity
R Carr et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
An enzyme library approach to biocatalysis: Development of nitrilases for enantioselective production of carboxylic acid derivatives
G DeSantis et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene
T Bosma et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2002)
Increasing the precision of comparative models with YASARA NOVA - a self-parameterizing force field
E Krieger et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2002)
Improved stability of halohydrin dehalogenase from Agrobacterium radiobacter AD1 by replacement of cysteine residues
LX Tang et al.
ENZYME AND MICROBIAL TECHNOLOGY (2002)
Engineering cytochrome P450BM-3 for oxidation of polycyclic aromatic hydrocarbons
QS Li et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2001)
Development of an Escherichia coli whole cell biocatalyst for the production of L-amino acids
B Wilms et al.
JOURNAL OF BIOTECHNOLOGY (2001)
The consensus concept for thermostability engineering of proteins
M Lehmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY (2000)
Diversity of microbial threonine aldolases and their application
JQ Liu et al.
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC (2000)
The synthesis of chiral cyanohydrins by oxynitrilases
H Griengl et al.
TRENDS IN BIOTECHNOLOGY (2000)
Oxynitrilases for asymmetric C-C bond formation
DV Johnson et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2000)