Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 353, Issue 16, Pages 2905-2909Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201100395
Keywords
asymmetric catalysis; catalyst recycling; domino reactions; Henry reaction; Michael addition
Categories
Funding
- Robert A. Welch Foundation [T-1460]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [0851966] Funding Source: National Science Foundation
Ask authors/readers for more resources
A new type of pyrrolidine-based organocatalyst has been developed and found to be very effective for the domino Michael/Henry reaction in aqueous solvents. For the reaction involving pentane-1,5-dial and various nitroolefins, good yields (6585%) and excellent enantioselectivities (99%) were obtained using this catalyst. In addition, the catalyst could be recycled up to four times resulting in good yields and up to seven times with good enantioselectivity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
