4.7 Article

Morpholinium Trifluoroacetate-Catalyzed Aldol Condensation of Acetone with both Aromatic and Aliphatic Aldehydes

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 352, Issue 7, Pages 1135-1138

Publisher

WILEY-BLACKWELL
DOI: 10.1002/adsc.200900902

Keywords

aldehydes; aldol condensation; amine salts; enones; organocatalysis

Funding

  1. Max-Planck-Society
  2. Deutsche Forschungsgemeinschaft [SPP 1179]
  3. Fonds der Chemischen Industrie

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We report a highly efficient, general and practical method for the aldol condensation of acetone with aromatic and aliphatic aldehydes, using morpholinium trifluoroacetate as a catalyst.

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