4.7 Article

Synthesis of β-Trifluoromethylated Δ1-Pyrrolines

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 352, Issue 16, Pages 2825-2830

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000487

Keywords

enones; fluorine; Michael addition; pyrrolines; Schiff bases

Funding

  1. Bayer CropScience Co.

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Trifluoromethylated Delta(1)-pyrrolines have been easily synthesized in a one-pot procedure from beta-(trifluoromethyl)enones. These substrates are valuable building blocks for further syntheses. For ex-ample, trifluoromethylated prolines have been obtained.

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