4.7 Article

Efficient and General Continuous-Flow Hydroarylation and Hydroalkylation of Styrenes

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 352, Issue 17, Pages 2961-2965

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000538

Keywords

continuous-flow microwave conditions; flow reactor; green chemistry; heterogeneous catalysis; polymerization

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A simple and efficient continuous-flow hydroarylation of arenes and heteroarenes using various styrenes in conjunction with a heterogeneous catalyst has been developed. Additionally, this method has been successfully extended to the hydroalkylation of styrenes by employing 1,3-dicarbonyl compounds as the nucleophile. Multigram quantities of diarylmethanes have been prepared using this new flow method.

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