4.7 Article

Selective C3-C3 Oxidative Cross-Coupling between Unactivated Anilines and Indoles

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 352, Issue 18, Pages 3230-3234

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000603

Keywords

aromatic substitution; biaryls; C-C coupling; oxidation; regioselectivity

Funding

  1. National Natural Science Foundation of China [21072033]
  2. Fudan University

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A selective C3-C3 oxidative cross-coupling between unactivated anilines and indoles catalyzed by copper bromide together with iodobenzene diacetate as the oxidant is described. This methodology provides a novel approach to biaryl synthesis.

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