4.7 Article

Development of a Mild Procedure for the Addition of Bisulfite to Electrophilic Olefins

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 352, Issue 18, Pages 3163-3168

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201000543

Keywords

alkenes; amine catalysis; sulfonic acids; thia-Mchael addition; triethylamine

Funding

  1. Enterprise-Ireland
  2. PTRLI cycle III

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The sulfonylation of activated alkenes is an important yet unexplored reaction due to the harshness of conditions required. We have identified a procedure which allowed the reaction of alkenes with equimolar amounts of bisulfite at room temperature.

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