Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 351, Issue 13, Pages 2113-2123Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200900267
Keywords
amino alcohols; hydroaminomethylation; hydroformylation; hydrolysis; polyamines; polyamino alcohols
Categories
Ask authors/readers for more resources
In this contribution, the synthesis of a new class of chiral polyamino alcohols (PAA) via a two-step hydroaminomethylation/hydrolysis procedure is reported. The chiral polyamines are obtained by hydroaminomethylation of N-olefinic oxazolidinones with different amines in first step followed by hydrolysis of the resulting polyamines to give the chiral PAA in the second step. The dendritic chiral PAA (Mw = 1300-1400 g mol(-1)) are also synthesized efficiently through a multifold hydroaminomethylation/hydrolysis procedure. Furthermore, chiral PAA are investigated as ligands in ruthenium-catalyzed asymmetric hydrogen transfer reduction of acetophenone to 1-phenyl alcohol.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available