Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 351, Issue 7-8, Pages 963-983Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200800776
Keywords
alkynylation; catalytic asymmetric synthesis; propargylic alcohols; propargylic amines
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Funding
- National Science Foundation
- National Institutes of Health
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM033049] Funding Source: NIH RePORTER
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Over the past decade, large strides have been achieved in the invention of methods for the direct enantioselective addition of alkynes and metal alkynylide nucleophiles into prochiral aldehydes, ketones, and imines. This review highlights and compares the available methods for these transformations.
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