Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 351, Issue 17, Pages 2747-2763Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200900566
Keywords
arylation; catalysis; C-C coupling; olefination; palladium; perfluorinated substituents
Categories
Funding
- Deutsche Forschungsgemeinschaft
- Fonds der Chemischen Industrie
- Bayer Scherdng Pharma AG
Ask authors/readers for more resources
How much fluoride is good for a strong electron-withdrawing effect? In this review we summarize recent results on the use of perfluoroalkanesulfonates, in particular of the cost effective nonafluorobutanesulfonates (nonaflates), in transition metal-catalyzed reactions and a few other typical transformations. During the last decade many advantages over the commonly used triflates have been discovered. The generation of alkenyl and (het)aryl nonaflates and their applications in metal-catalyzed processes such as Heck, Suzuki, Sonogashira, Stille, and Negishi couplings or amination reactions are described. Although far from a systematic investigation, all the presented results clearly demonstrate the many advantages of nonaflates and of similar higher fluorinated sulfonates in laboratory and industrial scale organic synthesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available