Journal
ADVANCED MATERIALS
Volume 26, Issue 43, Pages 7393-7398Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201403562
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Funding
- National Science Foundation of China [20874015, 51273047]
- Shu Guang project - Shanghai Municipal Education Commission [12SG07]
- Shanghai Education Development Foundation
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A strategy to prepare doxorubicin-loaded magnetic silk fibroin nanoparticles is presented. The nanoparticles serve as a nanometer-scale drug-delivery system in the chemotherapy of multidrug-resistant cancer under the guidance of a magnetic field. The magnetic tumor-targeting ability broadens the range of biomedical applications of silk fibroin, and the nanoparticle-assisted preparation strategy is useful for the advancement of other biomacromolecule-based materials.
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