Journal
ADVANCED MATERIALS
Volume 26, Issue 32, Pages 5633-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201400831
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Funding
- National Research Foundation (NRF), Prime Minister's Office, Singapore under its NRF Fellowship [NRF2009NRF-RF001-015]
- Campus for Research Excellence and Technological Enterprise (CREATE) programme-Singapore Peking University Research Centre for a Sustainable Low-Carbon Future
- NTU-A*Star Centre of Excellence for Silicon Technologies (A*Star SERC) [112 351 0003]
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An inclusion complex of NaYF4:Yb3+, Er3+ upconversion nanoparticles with a cyclodextrin in aqueous conditions exhibits luminescence quenching when excited at 980 nm. This non-radiative relaxation leads to an unprecedented photoacoustic signal enhancement. In vivo localization of alpha-cyclodextrin-covered NaYF4:Yb3+, Er3+ is demonstrated using photoacoustic tomography in live mice, showing its high capability for photoacoustic imaging.
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