4.8 Article

Drug Delivery with PEGylated MoS2 Nano-sheets for Combined Photothermal and Chemotherapy of Cancer

Journal

ADVANCED MATERIALS
Volume 26, Issue 21, Pages 3433-3440

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201305256

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MoS2 nanosheets functionalized with poly ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near-infrared absorbance of MoS2, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration.

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