Journal
ADVANCED MATERIALS
Volume 26, Issue 28, Pages 4794-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201400158
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Funding
- National Natural Science Foundation of China [51222203]
- National 973 Program of China [2011CB911002, 2012CB932601]
- Juangsu Natural Science Fund for Distinguished Young Scholars
- Priority Academic Program Development of Jiangsu Higher Education Institutions
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Red blood cells are attached to iron oxide nanoparticles pre-coated with chlorine e6, a photosensitizer, and then loaded with a chemotherapeutic drug, doxorubicin, to enable imaging-guided combined photodynamic and chemotherapy of cancer, achieving excellent synergistic therapeutic effects in an animal tumor model. This work highlights the great promise of integrating cell-based drug-delivery systems with nanotechnology as a biocompatible multifunctional platform for applications in cancer theranostics.
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