4.8 Article

Bioelectronic Light-Gated Transistors with Biologically Tunable Performance

Journal

ADVANCED MATERIALS
Volume 27, Issue 5, Pages 831-836

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201403988

Keywords

bioelectronics; silicon nanowire field-effect transistors (FETs); bacteriorhodopsin; biological regulation; ionophores

Funding

  1. U.S. Department of Energy, the Office of Basic Energy Sciences, the Division of Materials Sciences and Engineering
  2. U.S. Department of Energy [DE-AC52-07NA27344]
  3. Office of Science, Office of Basic Energy Sciences, of the U.S. Department of Energy [DE-AC02-05CH11231]
  4. LSP program at LLNL

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Light-activated bioelectronic silicon nanowire transistor devices are made by fusing proteoliposomes containing a bacteriorhodopsin ( bR) proton pump onto the nanowire surface. Under green-light illumination, bR pumps protons toward the nanowire, and the pH gradient developed by the pump changes the transistor output. Furthermore, co-assembly of small biomolecules that alter the bilayer permeability to other ions can upregulate and downregulate the response of fieldeffect transistor devices.

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