4.8 Article

Nanoparticles Mimicking Viral Surface Topography for Enhanced Cellular Delivery

Journal

ADVANCED MATERIALS
Volume 25, Issue 43, Pages 6233-6237

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201302737

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Funding

  1. Australian Research Council
  2. Queensland Cancer Council
  3. Queensland Government

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Novel silica nanoparticles mimicking virus surface topography are prepared. It is demonstrated that increases in nanoscale surface roughness promote both binding of biomolecules and cellular uptake; thus, the cellular delivery efficiency is significantly increased (scale bars 20 mu m).

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