Journal
ADVANCED MATERIALS
Volume 25, Issue 23, Pages 3202-3208Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201300525
Keywords
anisotropic etching; hydrophobic cavities; nanocontainers; magnetic resonance imaging; theranostics
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Funding
- NRF [2010-0014807, 2010-0020648, 2010-0020209, 2010-0019923]
- MIHWAF (the Korea Health 21 RD Project) [A085136]
- KRIBB Research Initiative Program
- iNtRON biotechnology
- Korea Health Promotion Institute [A085136] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2010-0014807, 2010-0020209] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Hollow Mn-doped iron oxide nanocontainers, formed by a novel one-pot synthetic process, fulfill the dual requirements of delivering an effective dose of an anticancer drug to tumor tissue and enabling image-contrast monitoring of the nanocontainer fate through T-2-weighted magnetic resonance imaging, thereby determining the optimal balance between diagnostic and therapeutic moieties in an all-in-one theranostic nanoplatform.
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