4.8 Article

Electrolyte-Gated Organic Field-Effect Transistor Sensors Based on Supported Biotinylated Phospholipid Bilayer

Journal

ADVANCED MATERIALS
Volume 25, Issue 14, Pages 2090-2094

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201203587

Keywords

electronic sensing; organic field-effect transistors; electrolyte-gated organic field-effect transistors

Funding

  1. Electrolyte-Gated Organic Field-Effect Biosensors- BioEGOFET project, SEVENTH FRAMEWORK PROGRAMME [248728]
  2. Gas Sensors on Flexible Substrates for Wireless Applications-FlexSMELL project, SEVENTH FRAMEWORK PROGRAMME [2009-238454]
  3. Italian Ministry of Education, University and Research (MIUR) [2009AZKNJ7]

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Anchored, biotinylated phospholipids forming the capturing layers in an electrolytegated organic field-effect transistor (EGOFET) allow label-free electronic specific detection at a concentration level of 10 nM in a high ionic strength solution. The sensing mechanism is based on a clear capacitive effect across the PL layers involving the charges of the target molecules.

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