Journal
ADVANCED MATERIALS
Volume 24, Issue 11, Pages 1418-1423Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201104714
Keywords
silica-coated gold nanorods; theranostics; light-controlled drug release; chemotherapy; hyperthermia
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Funding
- National Basic Research Program of China [2010CB93404, 2011CB933401, 2012CB93401]
- National Natural Science Foundation of China [31070854]
- Major National ST Program
- Chinese Academy of Sciences
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X. Wu, C. Chen, and co-workers develop mesoporous silica-coated gold nanorods (Au@ SiO2) as a versatile platform for imaging, chemotherapeutics, and hyperthermia. The Au@ SiO2 thus keeps both the unique functions of mesoporous silica nanoparticles and gold nanorods, and also provides a new functionality: lightcontrolled drug release. With integrated functions, such multifunctional theranostic systems are critical to optimize therapeutic efficacy and to improve safety of therapeutic regimes. They will provide more opportunities for on-demand therapy, paving the way to personalized medicine.
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