Journal
ADVANCED MATERIALS
Volume 25, Issue 6, Pages 922-927Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201203826
Keywords
hydrophobic interaction; surface chemistry; cell recognition; thermoresponsive materials; nanostructures
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Funding
- National Research Fund for Fundamental Key Projects [2012CB933800, 2011CB935700, 2012CB933200]
- National Natural Science Foundation [21175140, 20974113, 21121001]
- Chinese Academy of Sciences [KJZD-EW-M01]
- China Postdoctoral Science Foundation [20110490602]
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Capture and release of cancer cells: a thermoresponsive nanostructured surface is designed to reversibly capture and release cancer cells, wherein hydrophobic interaction helps the realization of target capture/release of cancer cells. The unique nature of the designed platform is based on the synergistic effect of hydrophobic interactions between the smart surface and the hydrophobic anchor (i.e., biotin-BSA), and topographic interactions between the nanostructured substrates and cancer cells.
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