Journal
ADVANCED MATERIALS
Volume 24, Issue 11, Pages 1466-1470Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201103501
Keywords
hydrogels; interfaces; spatial control; tissue engineering
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Funding
- NIH [1 DP2 OD006499-01]
- King Abdulaziz City for Science and Technology
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An adaptable density gradient multilayer polymerization (DGMP) method facilitates simple fabrication of complex multicompartment scaffolds with structurally continuous interfaces. Solvent density liquid-liquid phase segregation compartmentalizes varied mechanical and chemical cues independently. Bulk photopolymerization produces stratified three-dimensional and two-dimensional matrices. Cells attach to patterned adhesion peptides on biomimetic 2D substrates.
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