4.8 News Item

Biologically Responsive Polymeric Nanoparticles for Drug Delivery

Journal

ADVANCED MATERIALS
Volume 24, Issue 28, Pages 3878-3886

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201200420

Keywords

responsive system; triggered drug delivery; nanoparticles; pH; oxidation

Funding

  1. Division Of Materials Research
  2. Direct For Mathematical & Physical Scien [1006601] Funding Source: National Science Foundation
  3. NCI NIH HHS [R25 CA153955] Funding Source: Medline

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Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.

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