Journal
ADVANCED MATERIALS
Volume 24, Issue 31, Pages 4271-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201201232
Keywords
microfluidic spinning; fibers; microstructures; patterned; ribbons; grooved; cell alignment; alginates
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Funding
- National Research Lab (NRL) program, the Korea Science and Engineering Foundation (KOSEF), Republic of Korea [20110020455]
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Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.
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