Journal
ADVANCED MATERIALS
Volume 24, Issue 13, Pages 1748-1754Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201104070
Keywords
quantum dots; graphene; fluorescence; photothermal therapy; nanocomposites
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Funding
- National Science Council of the Republic of China, Taiwan [NSC100-2320-B-009-006-MY2, NSC 99-2221-E-009-070-MY3]
- National Chiao Tung University
- Ministry of Education, Taiwan, R.O.C
- Army Medical Research & Material Command [W81XWH-10-1-0320, W81XWH-10-1-0604]
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Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.
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