4.8 Article

Nanoemulsion Composite Microgels for Orthogonal Encapsulation and Release

Journal

ADVANCED MATERIALS
Volume 24, Issue 28, Pages 3838-3844

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201200214

Keywords

hydrogels; microfluidics; microgels; nanoemulsions; drug delivery

Funding

  1. Novartis-MIT Center for Continuous Manufacturing
  2. Institute for Collaborative Biotechnologies through U.S. Army Research Office [W911NF-09-0001]
  3. National Science Foundation [CMMI-1120724, DMR-1006147]
  4. Division Of Materials Research
  5. Direct For Mathematical & Physical Scien [1006147] Funding Source: National Science Foundation
  6. Div Of Civil, Mechanical, & Manufact Inn
  7. Directorate For Engineering [1120724] Funding Source: National Science Foundation

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Crosslinkable nanoemulsions are combined with flow lithography for the synthesis of structured composite microgels with controlled hydrophobic compartments. The microgels are used to demonstrate a number of motifs for controlled encapsulation and release of active compounds, including small molecules, proteins, and nanoparticles, from a single material platform.

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