Journal
ADVANCED MATERIALS
Volume 23, Issue 24, Pages H178-H183Publisher
WILEY-BLACKWELL
DOI: 10.1002/adma.201004625
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Funding
- AFOSR Multidisciplinary University Research Initiative [FA9550-05-1-0346]
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3D biomimetic microvascular networks of nearly arbitrary design are patterned by omnidirectional printing of a fugitive organic ink into a photopolymerizable hydrogel matrix. This novel approach hinges critically on tailoring the chemical and rheological properties of the fugitive ink as well as the photopolymerizable hydrogel reservoir and fluid filler. These hydrogel-based, microvascular constructs may find potential application in 3D cell culture, tissue engineering, organ modeling, and autonomic healing.
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