Journal
ADVANCED MATERIALS
Volume 24, Issue 4, Pages 492-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201103794
Keywords
thrombin; tannic acid; layer-by-layer assembly; bleeding; hemostasis
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Funding
- U.S. Army Research Office [W911NF-07-D-0004]
- Ferrosan Medical Devices A/S (Soeborg, Denmark)
- National Science Foundation
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Spray layer-by-layer assembly is used to create hemostatic films containing thrombin and tannic acid. The spray assembly technique enables coating of porous and absorbent commercial gelatin sponges with these films. Coated sponges are able to promote instantaneous hemostasis in a porcine spleen bleeding model.
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