Journal
ADVANCED MATERIALS
Volume 23, Issue 21, Pages 2436-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201100351
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Funding
- Ministry of Health & Welfare, Republic of Korea [A085136]
- Ministry of Education, Science and Technology [2009-0084190]
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pH-sensitive drug-delivering magnetic nanoparticles (DMNPs) have been developed as theragnostic nanocarriers that release doxorubicin (DOX) under acidic conditions within cancer cells. The drug release kinetics of the DMNPs, combined with the nanoparticle accumulation pattern in tumor cells, can be monitored by magnetic resonance imaging (MRI) to guide decisions regarding the optimization of drug dosing schedules.
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