4.8 Article

Cytophilic Fluorescent Bioprobes for Long-Term Cell Tracking

Journal

ADVANCED MATERIALS
Volume 23, Issue 29, Pages 3298-3302

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201101714

Keywords

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Funding

  1. Research Grants Council of Hong Kong [603509, HKUST2/CRF/10]
  2. Innovation and Technology Commission [ITP/008/09NP]
  3. University Grants Committee of Hong Kong [AoE/P-03/08]
  4. National Science Foundation of China [20974028]

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Molecules of siloles are almost non-fluorescent but their nanoaggregates are highly emissive, exhibiting aggregation-induced emission (AIE). The AIE-active aggregates are cytocompatible with living cells, stain cytoplasms of HeLa cells indelibly without contaminating another type of cell line in a co-culture system, and remain visible for a long period of time.

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