Journal
ADVANCED MATERIALS
Volume 23, Issue 24, Pages H200-H204Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201100600
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Funding
- Agence Nationale pour la Recherche [ANR-07-NANO-002]
- MESR
- Institut Universitaire de France
- FWO Flanders
- UGent (BOF)
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A versatile method to selectively encapsulate water-insoluble molecules in the nanoshell of layer-by-layer capsules made exclusively of polysaccharides is described. This relies on the very high affinity of hydrophobic molecules for an alkylated hyaluronic acid used as a polyanionic partner of a chitosan derivative for the capsule synthesis. The hydrophobic molecules entrapped in the nanoshell can be delivered intracellularly in dendritic cells.
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