Journal
ADVANCED MATERIALS
Volume 23, Issue 13, Pages 1550-1553Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201003744
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Funding
- National Institutes of Health [R01-GM065918]
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High-resolution patterns of proteins at multiple length scales are printed by a facile and flexible strategy using a flat elastomeric stamp and direct covalent immobilization onto mixed self-assembled monolayers of tri(ethylene glycol)- and carboxylic acid-hexa(ethylene glycol)terminated alkanethiols on gold-coated substrates. This is a robust method for generating complex protein arrays with precise control over micrometer- and nanometer-scale pattern geometries while maintaining a protein-adsorption-resistant background.
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