Journal
ADVANCED MATERIALS
Volume 22, Issue 42, Pages 4736-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201001436
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Funding
- NSF FIBR [EF-0526854]
- State of Utah Centers of Excellence Program
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Bioprinting consists of automated deposition of cells and biomaterials to mimic the architecture of a tissue. Gold nanoparticles act as dynamic, multivalent crosslinkers for thiol-modified hyaluronic acid and gelatin. The resulting synthetic extracellular matrix can be bioprinted into tubular constructs that support cell proliferation and matrix remodeling. The figure shows a view of a tissue construct (containing a fluorescent dye) in the x-y plane, and the inset shows the print head used.
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