Journal
ADVANCED MATERIALS
Volume 22, Issue 37, Pages 4186-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201001544
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Funding
- National University of Singapore [ARF R-279-000-234-101, R279-000-301-646]
- Singapore Ministry of Education [R-279-000-255-112]
- Ministry of Defense [R-279-000-301-232]
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A water-soluble organic/niorganic hybrid nanodot based on polyhedral oligomeric silsesquioxane (POSS) and conjugated oligoelectrolyte is designed and synthesized for two-photon fluorescence imaging of cellular nucleus, which takes advantage of its small size (similar to 3.3 nm) that imparts nucleus permeability and substantial DNA-enhanced two-photon excited fluorescence that allows illuminating the nucleus with a high contrast.
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