4.8 Article

Specific Protein Detection Using Thermally Reduced Graphene Oxide Sheet Decorated with Gold Nanoparticle-Antibody Conjugates

Journal

ADVANCED MATERIALS
Volume 22, Issue 32, Pages 3521-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201000520

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Funding

  1. US NSF [CMMI-0900509, CBET-0803142, ECCS-0708998]
  2. US Department of Energy [DE-AC02-06CH11357]
  3. Directorate For Engineering
  4. Div Of Civil, Mechanical, & Manufact Inn [0900509] Funding Source: National Science Foundation

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A highly sensitive and selective field-effect transistor biosensor using thermally reduced graphene oxide (TRGO) sheet decorated with gold nanoparticle-antibody conjugates is demonstrated. Probe antibody (anti-Immunoglobulin G) is labeled on the surface of the TRGO sheet through gold nanoparticles and electrical detection of the protein binding (Immunoglobulin G and anti-Immunoglobulin G) is accomplished by FET and dc measurements.

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