4.8 Article

High-Strength Hydrogels with Integrated Functions of H-bonding and Thermoresponsive Surface-Mediated Reverse Transfection and Cell Detachment

Journal

ADVANCED MATERIALS
Volume 22, Issue 24, Pages 2652-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200904016

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Funding

  1. National Natural Science Foundation of China [30770587]
  2. Program for New Century Excellent Talents in University

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The construction of a high-strength hydrogel with integrated functions by photo-initiated copolymerization of temperature-sensitive and hydrogen-bonding monomers is described. The hydrogen-bonding and thermoresponsive surface of hydrogels offers a multifunctional platform, where reverse gene transfection and gene-modified cell detachment can be achieved for the potential use in the regeneration and replacement of soft tissue.

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