Journal
ADVANCED MATERIALS
Volume 22, Issue 43, Pages 4831-+Publisher
WILEY-BLACKWELL
DOI: 10.1002/adma.201001855
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Funding
- Natural Sciences and Engineering Research Council (NSERC)
- Canadian Institute of Health Research (CIHR)
- Japanese long-term study abroad scholarship
- Canadian Council
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Primary endothelial cells are guided in an agarose hydrogel scaffold that is chemically patterned with an immobilized concentration gradient of VEGF165 using multiphoton laser patterning. It is particularly compelling that, in this 3D patterned hydrogel, endothelial cells differentiate to tip and stalk cells, having the morphology that is observed in vivo.
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