4.8 Article

Elastic Fully Three-dimensional Microstructure Scaffolds for Cell Force Measurements

Journal

ADVANCED MATERIALS
Volume 22, Issue 8, Pages 868-+

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200902515

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Funding

  1. Deutsche Forschungsgemeinschaft (DFG) [DFG-Fr 1671/4-3]
  2. State of Baden-Wurttemberg

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Elastic 3D scaffolds (see figure) are fabricated into a biocompatible photoresist using direct laser writing. These scaffolds can be rhythmically deformed by single beating cardiomyocytes and calibration with atomic force microscopy indicates that cellular forces down to 10-20 nN are detectable with the setup.

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