Journal
ADVANCED MATERIALS
Volume 22, Issue 46, Pages 5271-5275Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201002448
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Funding
- Nanyang Overseas Scholarship, Singapore
- NIH [EB001971]
- NSF Center for Science and Engineering of Materials
- Armed Forces Institute for Regenerative Medicine Wake Forest-Pittsburgh Consortium
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Protein-based biomaterials that promote rapid wound healing are prepared by expression of artificial genes in bacterial cells. Artificial extracellular matrix proteins containing full-length fibronectin domains 9 and 10 exhibit strong alpha(5)beta(1) integrin binding and support rapid spreading, proliferation, and collective migration of fibroblasts.
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